原著論文
Riyuji Yamashita, Shohei Fujii, Ryo Ushioda, & Kazuhiro Nagata
Ca2+ imbalance caused by ERdj5 deletion affects mitochondrial fragmentation
Scientific Reports Volume 11, Article number: 20772 (2021)
Shinya Ito, Kazuhiro Nagata
Quality Control of Procollagen in Cells
Annu Rev Biochem. 90:631-658 (2021)
Yuxia Zhanga, Michio Inoue, Akihisa Tsutsumi, Satoshi Watanabe, Tomohiro Nishizawac, Kazuhiro Nagata, Masahide Kikkawa and Kenji Inaba
Cryo-EM structures of SERCA2b reveal the mechanism of regulation by the luminal extension tail
Science Advance 6(33) eabb0147 (2020)
doi.org/10.1101/2020.03.28.012849.
A. Kohler, M. Morgelin, J.M. Gebauer, S. Ocal, T. Imhof, M. Koch, K. Nagata, M. Paulsson, M. Aumailley, U. Baumann, F. Zacke & G. Sengle:
New specific Hsp47 functions in collagen subfamily chaperoning.
FASEB J. 34:12040-12052 (2020)
https://faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202000570R
Yo-hei Yamamoto, Ayano Kasai, Hiroko Omori, Tomoe Takino, Munechika Sugihara, Tetsuo Umemoto, Maho Hamasaki, Tomohisa Hatta, Tohru Natsume, Richard I. Morimoto, Ritsuko Arai, Satoshi Waguri, Miyuki Sato, Ken Sato, Shoshana Bar-Nun,Tamotsu Yoshimori, Takeshi Noda and Kazuhiro Nagata
ERdj8 governs the size of autophagosomes during the formation process
J. Cell. Biol. 219(8): e201903127 (2020)
M. Yoshida, M. Saito, S. Ito, K. Ogawa, N. Goshima, K. Nagata & T. Doi
Structure-Activity Relationship Study on Col-003, a Protein-Protein Interaction Inhibitor between Collagen and Hsp47.
Chem Pharm Bull. 68(3):220-226 (2020)
https://www.jstage.jst.go.jp/article/cpb/68/3/68_c19-00634/_article
G. Xiong, J. Chen, G. Zhang, S. Wang, K. Kawasaki, J. Zhu, Y. Zhang, K. Nagata, Z. Li, BP. Zhou, R. Xu
Hsp47 promotes cancer metastasis by enhancing collagen-dependent cancer cell-platelet interaction.
Proc Natl Acad Sci U S A. 117 (7) :3748-3758 (2020)
doi.org/10.1073/pnas.1911951117
S. Ito, M. Saito, M. Yoshida, K. Takeuchi, T. Doi & K. Nagata
A BRET-based assay reveals collagen-Hsp47 interaction dynamics in the endoplasmic reticulum and small-molecule inhibition of this interaction.
J Biol Chem. 294(44):15962-15972 (2019)
doi: 10.1074/jbc.RA119.010567
KK. Fujii, Y. Taga, T. Sakai, S. Ito, S. Hattori, K. Nagata & T. Koide
Lowering the culture temperature corrects collagen abnormalities caused by HSP47 gene knockout.
Sci Rep.9(1):17433. (2019)
DOI:10.1038/s41598-019-53962-0
H. Khalil, O. Kanisicak, RJ. Vagnozzi, AK. Johansen, BD. Maliken, V. Prasad, JG. Boyer, MJ. Brody, T. Schips, KK. Kilian, RN. Correll, K. Kawasaki, K. Nagata & JD. Molkentin
Cell-specific ablation of Hsp47 defines the collagen-producing cells in the injured heart.
JCI Insight 4(15):e128722 (2019)
M. Inoue, N. Sakuta, S. Watanabe, Y. Zhang, K. Yoshikaie, R. Ushioda, Y. Kato, J. Takeda, T. Tsukazaki, K. Nagata & K. Inaba
Structural Basis of Sarco/Endoplasmic Reticulum Ca2+-ATPase 2b Regulation via Transmembrane Helix Interplay
Cell Rep.27(4)1221-1230 (2019)
10.1016/j.celrep.2019.03.106
https://www.sciencedirect.com/science/article/pii/S221112471930453X
S. Ito & K. Nagata
Roles of the endoplasmic reticulum-resident, collagen-specific molecular chaperone Hsp47 in vertebrate cells and human disease.
J Biol Chem. 294(6):2133-2141 (2019)
DOI: 10.1074/jbc.TM118.002812
M. Sugihara, D. Morito, S. Ainuki, Y. Hirano, K. Ogino, A. Kitamura, H. Hirata & K. Nagata
The AAA+ ATPase/ubiquitin ligase mysterin cytoplasmic lipid droplets
J. Cell. Biol. 218(3):949-960 (2019)
DOI: 10.1083/jcb.201712120 | Published January 31, 2019
R. Ushioda & K. Nagata
Redox-Mediated Reguiatory Mechanisms of Endplasmic Reticulum Homeostasis.
Cold Spring Harbor Perspectives in Biology”Protein Homeostasis SECOND EDITION”
Cold Spring Harbor Laboratory press 1;11(5), (2019)
doi: 10.1101/cshperspect.a033910
H.H. Kampinga, C. Andreasson, A. Barducci, M.E.Cheetham, D. Cyr, C. Emanuelsson, P. Genevaux, J.E. Gestwicki, P. Goloubinoff, J. Huerta-Cepas, J. Kirstein, K. Liberek, M.P. Mayer, K. Nagata, N.B. Nillegoda, P. Pulido, C. Ramos, P. De Los Rios, S. Rospert, R. Rosenzweig, C. Sahi, M. Taipale, B. Tomiczek, R. Ushioda, J.C. Young,R. Zimmermann, A. Zylicz, M. Zylicz, E.A. Craig & J. Marszalek
Function, evolution, and structure of J-domain proteins.
Cell Stress and Chaperones 24(1):7-15 (2019)
doi: 10.1007/s12192-018-0948-4. Epub 2018 Nov 26.
https://link.springer.com/article/10.1007%2Fs12192-018-0948-4